From car registration fees, to health care and carbon monoxide detectors to collecting DNA, a slew of new laws are set to take effect Wednesday.

Dozens of drivers packed the DMV office at Mesa Mall Tuesday, trying to register their cars before their tags expired -- and before they'll have to shell out more cash to do so. Starting July 1, car registration fees will go up $32 for owners of standard cars and SUVs.

State leaders who supported the law, known as the FASTER plan, say it will generate $250 million dollars a year to fund repairs to bridges and roads that C-DOT has deemed unsafe. They say it will also save $8,000 construction jobs in the state.

Opponents say it asks too much of Colorado drivers during a time when every penny is important. They also feel it contradicts another law that goes into effect Wednesday, that will allow state leaders to direct money that usually goes into the state's transportation fund to other areas.

Registration fees will increase $41 over the next three years.

A new law that was sponsored by Grand Junction Representative Steve King will also go into effect Wednesday. Under "Katie's Law" any person arrested for a felony crime will have to submit a DNA sample via mouth swab. If that person is later charged for those crimes, that DNA sample will be entered into a statewide database.

State leaders say it will help authorities solve cases, help prosecutors put criminals away, and keep criminals from becoming repeat offenders.

A new law that some state leaders hail as the most significant health care reform in Colorado history also goes into effect July 1. Under the Colorado Health Care Affordability Act, the state will generate $600 million in provider fees from hospitals, which will be matched by the federal government.

Officials say that money will be used to expand medicaid and CHP+ programs in the state and increase medicaid reimbursement to hospitals.

Supporters say it will provide health care to more than 100 thousand uninsured Coloradans. Opponents fear it will add to the national debt and force hospitals to pass the cost of the provider fee onto the patient.

Other laws that take effect July 1 deal with protecting homeowners and small businesses, requiring carbon monoxide detectors in new homes, expanding eligibility for unemployment benefits, and making penalties for internet sex crimes tougher.