BOSTON (AP) - Dante Cunningham scored 14 points with 11 rebounds and third-seeded Villanova beat Duke for the first time in more than 50 years, taking advantage of the Blue Devils' poor shooting to win 77-54 Thursday night and advance to the NCAA Regional final.

The Wildcats (29-7) will play Big East rival Pittsburgh (31-4), the top seed in the East, on Saturday for a trip to the Final Four.

Duke (30-7), which spent a week at no. 1 in the nation earlier this season, failed to reach the round of eight for the fifth consecutive year.

Kyle Singler scored 15 and Jon Scheyer had 13 for the second-seeded Blue Devils. But Scheyer and Gerald Henderson combined to make just four of 32 attempts as Duke shot a season-low 26.7 percent from the floor.

(Copyright 2009 By The Associated Press. All Rights Reserved.)